abstract：:The low water permeability feature of original cellulosic membranes was considered an advantage in the absence of dialysis equipment that are capable of controlling water removal. The advent of ultrafiltration control systems led to the development and use of high-flux (HF) membranes that allowed improved middle molec...

journal_title：Blood purification

authors： Ronco C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Recent updates to the Nikkiso Aquarius continuous renal replacement therapy (CRRT) platform allowed us to develop a post-dilution protocol for regional citrate anticoagulation (RCA) using standard bicarbonate buffered, calcium containing replacement solution with acid citrate dextrose formula-A as a cit...

journal_title：Blood purification

authors： Kirwan CJ,Hutchison R,Ghabina S,Schwarze S,Beane A,Ramsay S,Thompson E,Prowle JR

更新日期：2016-01-01 00:00:00

abstract：:In previous reports of the Frequent Hemodialysis Network trials, frequent hemodialysis (HD) reduced extracellular fluid (ECF) and left ventricular mass (LVM), with more pronounced effects observed among patients with low urine volume (UVol). We analyzed the effect of frequent HD on interdialytic weight gain (IDWG) and...

journal_title：Blood purification

authors： Raimann JG,Chan CT,Daugirdas JT,Depner T,Gotch FA,Greene T,Kaysen GA,Kliger AS,Kotanko P,Larive B,Lindsay R,Rocco MV,Chertow GM,Levin NW,Frequent Hemodialysis Network (FHN) Trial Group.

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Dialysate fluid connection to the membrane in continuous dialysis may affect solute clearance. Although circuit connections are routinely made counter-current to blood flow in intermittent dialysis, no study has assessed the effect of this dialysate fluid flow direction on removal of small solutes creatinine...

journal_title：Blood purification

authors： Baldwin I,Baldwin M,Fealy N,Neri M,Garzotto F,Kim JC,Giuliani A,Basso F,Nalesso F,Brendolan A,Ronco C

更新日期：2016-01-01 00:00:00

abstract：:For maintenance hemodialysis (MHD) patients, the blood is in low hypercoagulable state due to the use of heparin or low molecular weight heparin during dialysis. It is not rare to see hematoma in the puncture site. In recent years, several cases have been reported of spontaneous kidney rupture, but no hip hematoma, le...

journal_title：Blood purification

authors： Ye M,Liu Y,Zhou L,Wang C,Fu X,Peng Y,Liu H

更新日期：2016-01-01 00:00:00

abstract：AIMS:The aim of the study was to clarify the relationship between serum ferritin and infectious risks. METHODS:We evaluated all hospital admissions due to infections, clinical biomarkers and nutrition status in 129 incident Japanese dialysis patients during a median follow-up of 38 months. RESULTS:Kaplan-Meier analys...

journal_title：Blood purification

authors： Kato S,Lindholm B,Yuzawa Y,Tsuruta Y,Nakauchi K,Yasuda K,Sugiura S,Morozumi K,Tsuboi N,Maruyama S

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Glycated hemoglobin is used to assess diabetic control although its accuracy in dialysis has been questioned. How does it compare to the Continuous Glucose Monitoring System (CGMS) in peritoneal dialysis (PD) patients? METHODS:We conducted a retrospective analysis of 60 insulin-treated diabetic patients o...

journal_title：Blood purification

authors： Qayyum A,Chowdhury TA,Oei EL,Fan SL

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Dialysis membrane has been implicated in selenium (Se) deficiency in hemodialysis (HD). Intradialytic Se removal into dialysate through different membranes was investigated. METHODS:We studied 19 patients on standard HD with low-flux polysulfone membrane (group A), 10 patients on standard HD with ethyl...

journal_title：Blood purification

authors： Sonikian M,Dona A,Skarakis J,Trompouki S,Miha T,Karatzas I,Spiliopoulou C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Dyslipidemia is a common metabolic complication in patients with chronic kidney disease and is detected as changes in lipoprotein concentrations in serum. SUMMARY:Recently, other features of lipid abnormalities have been described, such as alterations in serum n-3 polyunsaturated fatty acids, cholesterol me...

journal_title：Blood purification

authors： Shoji T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:It was recently reported that the severity of coronary and carotid atherosclerosis in patients with end-stage kidney disease (ESKD) has improved over the last two decades. However, the frequency of coronary artery events observed at the initiation of dialysis remains high. SUMMARY:Recently, 5 different clin...

journal_title：Blood purification

authors： Tanaka Y,Joki N,Hase H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Standard low-flux haemodialysis (HD) is not very efficacious, and patient morbidity and mortality rates are still very high. According to the initial study design, the MPO study reported that high-flux HD (hf-HD) showed a significant 37% relative risk reduction of mortality in patients with serum albumin ≤4 ...

journal_title：Blood purification

authors： Locatelli F,Violo L,Longhi S,Del Vecchio L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Some angiotensin converting enzyme (ACE) inhibitors are efficiently removed from circulation by hemodialysis ('high dialyzability'), whereas others are not ('low dialyzability'). In patients receiving hemodialysis, this may influence the effectiveness of ACE inhibitors. METHODS:Using linked healthcare ...

journal_title：Blood purification

authors： Weir MA,Fleet JL,Dixon SN,Jain AK,Oliver M,Wald R,McIntyre C,Garg AX

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The number of patients receiving renal replacement therapy (RRT) increases annually and worldwide. Differences in the RRT incidence, prevalence, and modality vary between regions and countries for reasons yet to be clarified. AIMS:Gain a better understanding of the association between hemodialysis (HD)-rela...

journal_title：Blood purification

authors： Calice-Silva V,Hussein R,Yousif D,Zhang H,Usvyat L,Campos LG,von Gersdorff G,Schaller M,Marcelli D,Grassman A,Etter M,Xu X,Kotanko P,Pecoits-Filho R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemoadsorption may improve outcomes for sepsis by removing circulating cytokines. We tested a new sorbent used for hemoadsorption. METHODS:CTR sorbent beads were filled into columns of three sizes: CTR0.5 (0.5 ml), CTR1 (1.0 ml) and CTR2 (2.0 ml) and tested using IL-6 capture in vitro. Next, rats were ...

journal_title：Blood purification

authors： Zhang J,Peng Z,Maberry D,Volpe J,Kimmel JD,Federspiel WJ,Kellum JA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Bioelectrical impedance analysis (BIA) is a promising technique to evaluate dry weight. We compared the dry weight calculated by the three BIA equations Carlo Basile (CB) , Yanna Dou (YD) and the body composition spectroscopy (BCS) with clinical evaluation in maintenance hemodialysis (MHD) patients. METHODS...

journal_title：Blood purification

authors： Jian Y,Li X,Cheng X,Chen Y,Liu L,Tao Z,Zuo L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Frequent hemodialysis (HD) may be associated with an increased risk of vascular access complications. Studies addressing vascular access outcomes in frequent HD show conflicting results. METHODS:We searched Medline for trials looking at vascular access outcomes in frequent HD. RESULTS:Nineteen studies met ...

journal_title：Blood purification

authors： Cornelis T,Usvyat LA,Tordoir JH,Wang Y,Wong M,Leunissen KM,van der Sande FM,Kotanko P,Kooman JP

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Removal of protein-bound uremic toxins by dialysis therapy is limited. The effect of oral adsorbent AST-120 in chronic dialysis patients has rarely been investigated. METHODS:AST-120 was administered 6.0 g/day for 3 months in 69 chronic dialysis patients. The blood concentrations of indoxyl sulfate, p-creso...

journal_title：Blood purification

authors： Lee CT,Hsu CY,Tain YL,Ng HY,Cheng BC,Yang CC,Wu CH,Chiou TT,Lee YT,Liao SC

更新日期：2014-01-01 00:00:00

abstract：:Numerous experimental and clinical studies suggest that uric acid might have pathobiologic implications in the development and progression of hypertension, kidney disease, and coronary heart disease, among others, resulting in renewed interest in uric acid as a potential pathogenic mediator in these clinical condition...

journal_title：Blood purification

authors： Kanbay M,Solak Y,Gaipov A,Takir M,Weiner DE

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:N-Terminal pro-brain natriuretic peptide (NT-proBNP) is a predictor of cardiac events and death in the general population and in chronic kidney disease. There is limited information on how natriuretic peptides vary in dialysis patients. The aim of this study was to analyze NT-proBNP variability, factors...

journal_title：Blood purification

authors： Snaedal S,Qureshi AR,Carrero JJ,Heimbürger O,Stenvinkel P,Bárány P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Hypomagnesaemia is a cardiovascular (CV) risk factor in the general population. The aim of this study was to evaluate the relationship between pre-dialysis magnesium (Mg) and CV risk markers, [including pulse pressure (PP), left ventricular mass index (LVMI) and vascular calcifications (VC)], and mortality i...

journal_title：Blood purification

authors： João Matias P,Azevedo A,Laranjinha I,Navarro D,Mendes M,Ferreira C,Amaral T,Jorge C,Aires I,Gil C,Ferreira A

更新日期：2014-01-01 00:00:00

abstract：:The EUPHRATES trial (Evaluating Use of Polymyxin B Hemoperfusion in a Randomized Controlled Trial of Adults Treated for Endotoxemia and Septic Shock) is the first biomarker-driven trial in sepsis. This unique trial is being run in a blinded manner, further contributing to the robustness of its design. This paper will ...

journal_title：Blood purification

authors： Foster D,Klein DJ,Guadagni G,Walker PM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiovascular diseases (CVD) are the leading cause of mortality in hemodialysis (HD) patients. Recently, non-alcoholic fatty liver disease (NAFLD) has been recognized as a new risk factor for adverse CVD events in the general population. Our aim was to analyze the incidence of NAFLD in HD patients by u...

journal_title：Blood purification

authors： Mikolasevic I,Orlic L,Milic S,Zaputovic L,Lukenda V,Racki S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIMS:We aimed to examine the association between daily protein intake (DPI) and outcomes in patients from the Randomized Evaluation of Normal versus Augmented Level (RENAL) trial. METHODS:We analyzed the association between DPI and clinical outcomes using multivariable logistic regression, Cox proportio...

journal_title：Blood purification

authors： Bellomo R,Cass A,Cole L,Finfer S,Gallagher M,Lee J,Lo S,McArthur C,McGuinness S,Norton R,Myburgh J,Sheinkestel C,RENAL Study Investigators.

更新日期：2014-01-01 00:00:00

abstract：:On-line hemodiafiltration (ol-HDF) may improve clinical outcome in ESRD. The supposed mechanism is the improved clearance of uremic toxins by convective transport which is added to the diffusion transport. However, recent marked improvement in the performance of dialyzers has allowed higher removal rate of middle to l...

journal_title：Blood purification

authors： Kawanishi H

更新日期：2013-01-01 00:00:00

abstract：:To reduce the potential occurrence of hypotension during a dialysis treatment, intermittent infusion hemodiafiltration (I-HDF) using back filtration with an ultrapure dialysis fluid was developed. Under typical I-HDF treatment conditions, some 200-300 ml of ultrapure dialysis fluid was infused into the blood component...

journal_title：Blood purification

authors： Mineshima M,Eguchi K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Recent advances in nanotechnology have made it possible to mass-produce ultrathin silicon membranes with pore sizes in the range of nanometers. In this study, we investigate the possibility of employing ultrathin nanoporous silicon membranes with pore diameters of 5 and 20 nm for dialysis of human whole...

journal_title：Blood purification

authors： Ahmadi M,Gorbet M,Yeow JT

更新日期：2013-01-01 00:00:00

abstract：:Immune deficiency is one of the numerous consequences of chronic renal failure. We can hypothesize that an abnormal natural killer (NK) cell response is present in patients with end-stage renal disease (ESRD). To characterize the immune defect in ESRD patients, we performed a NK cell subset analysis in 66 patients wit...

journal_title：Blood purification

authors： Peraldi MN,Berrou J,Métivier F,Toubert A

更新日期：2013-01-01 00:00:00

abstract：:Many organic solutes accumulate in end-stage renal disease (ESRD) and some are poorly removed with urea-based prescriptions for hemodialysis. However, their toxicities have been difficult to assess. We have employed an animal model, the zebrafish embryo, to test the toxicity of uremic serum compared to control. Serum ...

journal_title：Blood purification

authors： Berman N,Lectura M,Thurman J,Reinecke J,Raff AC,Melamed ML,Reinecke J,Quan Z,Evans T,Meyer TW,Hostetter TH

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Fluid balance disorders are a relevant risk factor for morbidity and mortality in critically ill patients. Volume assessment in the intensive care unit (ICU) is thus of great importance, but there are currently few methods to obtain an accurate and timely assessment of hydration status. Our aim was to evalua...

journal_title：Blood purification

authors： Basso F,Berdin G,Virzì GM,Mason G,Piccinni P,Day S,Cruz DN,Wjewodzka M,Giuliani A,Brendolan A,Ronco C

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Anemia is a major complication of end-stage renal disease. Hemodialysis itself is regarded as a stimulus activating inflammation. Pro-inflammatory cytokines are able to suppress erythropoiesis. In this pilot study, we analyzed the changes in methylation status of promoters of immune response genes in cell-fr...

journal_title：Blood purification

authors： Korabecna M,Pazourkova E,Horinek A,Mokrejsova M,Tesar V

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Various cytokines are increased in hemodialysis (HD) patients, and are considered prognostic markers. Metabolic acidosis is common among chronic HD patients and is associated with survival. The relationship between acidosis and cytokines in HD patients has not been fully explored. The study aim was to measur...

journal_title：Blood purification

authors： Ori Y,Bergman M,Bessler H,Zingerman B,Levy-Drummer RS,Gafter U,Salman H

更新日期：2013-01-01 00:00:00

abstract：:The second law of thermodynamics applies with local exceptions to patient history and therapy interventions. Living things preserve their low level of entropy throughout time because they receive energy from their surroundings in the form of food. They gain their order at the expense of disordering the nutrients they ...

journal_title：Blood purification

authors： Ronco C

更新日期：2013-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a common complication in pediatric and neonatal intensive care units (ICU). Renal replacement therapy (RRT) is frequently needed in children in whom supportive therapy is not enough to satisfy their metabolic demands or to be able to provide adequate nutrition. The decision to begin dialys...

journal_title：Blood purification

authors： Bonilla-Félix M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Oxidative stress has been considered a nontraditional risk factor for cardiovascular disease in the chronic kidney disease (CKD) population, possibly triggered by uremic toxicity. METHODS:A chromatographic method with coulometric detection was adapted to directly and simultaneously determine cysteine (...

journal_title：Blood purification

authors： Rodrigues SD,Batista GB,Ingberman M,Pecoits-Filho R,Nakao LS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Carpal tunnel syndrome (CTS) is a common clinical presentation of dialysis-related amyloidosis. It was determined whether β(2)-microglobulin (β2M) and advanced glycation end products in serum are predictors of CTS in dialysis patients. METHODS:A total of 385 hemodialysis patients were screened for CTS....

journal_title：Blood purification

authors： Busch M,Schwenzky A,Franke S,Stein G,Wolf G

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Anticoagulation in hemodialysis (HD) patients at high risk of bleeding remains an intractable problem. Simulating endothelial cells by releasing anticoagulant on the membrane may be a promising alternative. METHODS:We modified a polyacrylonitrile (PAN) dialyzer by loading argatroban into its membrane a...

journal_title：Blood purification

authors： Zhang Y,Ning J,Veeraragoo P,Li Y,Dai S

更新日期：2012-01-01 00:00:00

abstract：:The number of geriatric patients on dialysis is increasing. This is due to demographic factors, a wider acceptance of elderly patients on dialysis, and an earlier start of dialysis in this patient group. Recent studies have questioned the effect of dialysis on quality of life in elderly patients with severe comorbidit...

journal_title：Blood purification

authors： Kooman JP,Cornelis T,van der Sande FM,Leunissen KM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The relationship between heart rate variability (HRV) and residual renal function (RRF) has not been elucidated previously. METHODS:In this cross-sectional study, HRV was evaluated in 71 peritoneal dialysis patients. Patients were divided into RRF decline group, RRF stable group and anuric group. RESULTS:R...

journal_title：Blood purification

authors： Tang W,Li LX,Pei J,Wang T

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The relationship between predialysis blood pressure (BP) and hemodialysis (HD) patient outcomes is controversial. We report the evolution of predialysis BP in incident patients treated with the dry weight method and its relationship with patients' outcomes. METHODS:Between January 2000 and 2009, 308 patient...

journal_title：Blood purification

authors： Chazot C,Vo-Van C,Deleaval P,Lorriaux C,Hurot JM,Mayor B,Jean G

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agent (ESA) resistance remains incompletely understood among hemodialysis (HD) patients. METHOD:A retrospective, multicenter study was designed to analyze data from 1,934 patients followed for up to two years. The outcome measure was the erythropoietin resistance index (ERI), defi...

journal_title：Blood purification

authors： Mallick S,Rafiroiu A,Kanthety R,Iqbal S,Malik R,Rahman M

更新日期：2012-01-01 00:00:00